Research

Companion Dx & Biomarker Discovery

Companion and Complimentary Diagnostics Companion diagnostics continue to play an ever expanding role in personalized healthcare as physician’s seek to better more accurately forecast patients’ potential responses to various treatment options. Whether you are a pharmaceutical company embarking on a new drug/Companion diagnostic offering or an independent Companion diagnostic manufacturer, our team can provide unparalled support to ensure expedient and successful parallel development of both your companion test and drug/biologic.

Genotyping Analysis (SNP)

Mutation Analysis: Single Nucleotide Poloymorphism (SNP) Mutations are genetic alterations either in germ or non-germ (somatic) cells. Mutations can impact the formation of various diseases as well as affect the response of a patient to particular drug treatments. The mutation can be an insertion, deletion, missense or nonsense mutation in the coding or non-coding regions. In some cases, a mutation occurs at the intron-exon boundary and affects the normal splicing of the transcript.

Expression Analysis

Gene Expression Services Scientists at Genome Explorations have worked with over 350 scientists worldwide in meeting their gene expression needs. As an industry leader in the microarray field and a certified provider of Affymetrix® microarray services and Life Technologies qPCR services, we have developed a series of SOPs that allow us to reproducibly generate global gene expression data sets of the highest quality. Our validated microarray protocols consistently result in sample-to-sample variability of less than 0.

Chromosomal Abnormality Analysis (FiSH)

Genomic Research Services

DEFINE, DESIGN, DISCOVER Our experienced scientists work one-on-one with scientists, researchers and clinicians to provide a ‘Complete Solution’ for Genotyping, Gene Expression and miRNA Profiling Services, from experimental design to in-depth data analysis and advanced bioinformatics. Our ‘Complete Solutions’ include state of the art Technologies from Illumina, Thermofisher Scientific and Affymetrix for challenging specimens, such as LCM, FFPE and whole blood samples. With over 40 years of combined experience, our scientists at Genome Explorations have developed detailed standard operating procedures (SOPs) that allow us to consistently generate the highest quality, most reproducible data sets in the industry.

Genomic Research Services

DEFINE, DESIGN, DISCOVER Our experienced scientists work one-on-one with scientists, researchers and clinicians to provide a ‘Complete Solution’ for Genotyping, Gene Expression and miRNA Profiling Services, from experimental design to in-depth data analysis and advanced bioinformatics. Our ‘Complete Solutions’ include state of the art Technologies from Illumina, Thermofisher Scientific and Affymetrix for challenging specimens, such as LCM, FFPE and whole blood samples. With over 40 years of combined experience, our scientists at Genome Explorations have developed detailed standard operating procedures (SOPs) that allow us to consistently generate the highest quality, most reproducible data sets in the industry.